Search results for "Seasonal Affective Disorder"
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Enhanced inflammatory and T-helper-1 type responses but suppressed lymphocyte proliferation in patients with seasonal affective disorder and treated …
2015
Abstract Background Animals show seasonal changes in the endocrine and immune system in response to winter stressors. Even though increased inflammation has been implicated in the pathophysiology of depression, whether immune disorder is a key mediator in seasonal affective depression (SAD) is unknown. Here, we hypothesized that short photoperiods in winter may induce inflammatory response, which contributes to SAD, and that light treatments should normalize immune function and improve depressive symptoms. Methods Twenty patients with a diagnosis of SAD, and a score on the HAM-29 of 20 or higher were recruited for this study. Twenty-one healthy subjects with no personal and family history o…
No changes in mood with the seasons: observations in 3000 chronic pain patients.
1999
Objective Seasonal affective disorder (SAD) and the theory of the effect of light on depression have gained some popularity in recent years. Research on epidemiology is largely based on retrospective measures asking explicitly for the experience of seasonal variations. Those measures have a low positive predictive value and do not enable us to distinguish between experience and belief. Method A consecutive sample of chronic pain patients filled out a depression questionnaire (CES-D) routinely as part of the diagnostic interview on becoming in-patients at a Pain Clinic in Mainz during a 5-year period. Results No support for seasonality or light effects was found. Conclusion The effect of lig…